{"product_id":"poly-prebiotic-powder","title":"Poly-Prebiotic Powder","description":"\u003cp\u003eA unique powdered blend of researched prebiotic fibers and polyphenols to support gastrointestinal, cellular, and immune function by boosting bifidobacteria and microbiome diversity*\u003c\/p\u003e\n\u003cbr\u003e\n\u003cdiv class=\"description product-description\" data-model=\"XLite\\Model\\Product\" data-identifier=\"56271\" data-property=\"description\"\u003e\n\u003cp\u003eA unique powdered blend of researched prebiotic fibers and polyphenols to support gastrointestinal, cellular, and immune function by boosting bifidobacteria and microbiome diversity*\u003c\/p\u003e\n\u003cdiv class=\"data-item-title active\"\u003e\u003cdiv\u003e\u003ch2\u003eBenefits \u0026amp; Features\u003c\/h2\u003e\u003c\/div\u003e\u003c\/div\u003e\n\u003cdiv class=\"data-item-content\"\u003e\u003cdiv class=\"product-detail-info\"\u003e\u003cdiv class=\"left\"\u003e\n\u003cdiv class=\"sub-content benifits\"\u003e\u003cul\u003e\n\u003cli\u003eSupports microbiome integrity and healthy G.I. function\u003csup\u003e*\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003eProvides immune system support\u003csup\u003e*\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003ePolyphenol and prebiotic combination boosts bifidobacteria and microbiome diversity\u003csup\u003e*\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003eTargets Bifidobacteria and Akkermansia muciniphila to support G.I. barrier function\u003csup\u003e*\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\u003c\/div\u003e\n\u003cdiv class=\"sub-content features\"\u003e\n\u003cul\u003e\n\u003cli\u003eBlend of researched prebiotics and polyphenols\u003c\/li\u003e\n\u003cli\u003ePleasant-tasting fruit flavor\u003c\/li\u003e\n\u003cli\u003eShelf-stable with low reported G.I. effects\u003c\/li\u003e\n\u003cli\u003ePart of the PureGI\u003csup\u003e\u0026amp;trade\u003c\/sup\u003e product line\u003c\/li\u003e\n\u003cli\u003eMade with high-quality vegan ingredients backed by verifiable science\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cdiv class=\"sub-content indications\"\u003e\n\u003ch2\u003eIndications\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eAges 18 and up\u003c\/li\u003e\n\u003cli\u003eMicrobiome integrity support\u003csup\u003e*\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003eCellular and immune system support\u003csup\u003e*\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cdiv class=\"data-item-content\"\u003e\u003cdiv class=\"product-detail-info\"\u003e\n\u003cdiv class=\"left\"\u003e\u003cdiv class=\"sub-content verifiable_science\"\u003e\n\u003ch2\u003eVerifiable Science\u003c\/h2\u003e\n\u003cp\u003ePrebiotics are nondigestible components of food that act to modulate and support the gut microbiota. Emerging evidence suggests that they may play an even more significant role than probiotics, performing beneficial metabolic, trophic and protective functions within the gut, leading to overall cellular, immune and metabolic support.\u003csup\u003e1\u003c\/sup\u003e Changes to the diet have been shown to alter microflora within just a few days. Restricted diets typically decrease microbiome diversity, while varied and diverse sources of fiber and polyphenols increase microbiome diversity. High microbiome diversity has been linked to optimal health and resilience.\u003csup\u003e2\u003c\/sup\u003e PreticX\u003csup\u003e™\u003c\/sup\u003e XOS (xylooligosaccharide) and BioEcolians\u003csup\u003e®\u003c\/sup\u003e a-GOS (alpha-glucooligosaccharide) both promote short-chain fatty acid (SCFA) production in the colon and Bifidobacteria in the G.I. tract. Bifidobacterium is the predominant intestinal bacterial genus during the first year of life and is associated with healthy immune development and cytokine balance both in infants and later in life.\u003csup\u003e3\u003c\/sup\u003e In a double-blind, randomized, placebo-controlled study, 32 healthy adult subjects were given 1.4 grams or 2.8 grams of PreticX\u003csup\u003e™\u003c\/sup\u003e XOS for eight weeks. The Bifidobacterium count increased 21% and 17% from baseline at Week \u003csup\u003e4\u003c\/sup\u003e and Week 8, respectively. In contrast to many common prebiotics, XOS, a-GOS and polyphenols report very low incidence of gas, bloating or other intestinal side effects.\u003csup\u003e4\u003c\/sup\u003e In an in vitro study using clinical isolates from hospital patients, XOS was found to stimulate growth in all 35 Bifidobacterium strains tested.\u003csup\u003e5\u003c\/sup\u003e While XOS promotes the SCFA butyrate, a major energy source for the colonocytes, a-GOS promotes propionate to support both glucose homeostasis and satiety. Studies show XOS also supports bowel motility, nutrient metabolism and emotional wellness. In a randomized, double-blind, placebo-controlled trial involving 25 subjects, supplementation with 2 grams of a-GOS was found to support abdominal comfort by Day 7.Supplementation continued to offer increasing support throughout the 28-day period, including bowel motility and stool consistency. A significant increase in \u003cem\u003eB. longum, B. animalis and lactobacilli \u003c\/em\u003ewas also reported. In addition, BioEcolians supplemented increased secretion in the mucosa of the antimicrobial peptide fl-defensins.\u003csup\u003e6\u003c\/sup\u003e These molecules moderate the adhesion of bacteria to the intestinal wall and support healthy cytokine balance in the intestine.\u003csup\u003e7\u003c\/sup\u003e The health benefits of polyphenols may be due to their effects on the microflora. These compounds, which are not completely absorbed, travel to the colon where bacteria convert them into easily absorbed metabolites. Polyphenols alsosupport healthy gut microbial composition.\u003csup\u003e8\u003c\/sup\u003e In an animal study involving mice on a high-fat, high-sucrose diet, supplementation with cranberry polyphenols promoted microflora balance, healthy fat metabolism in the liver, insulin sensitivity and cytokine balance, while supporting healthy weight management\u003csup\u003e†\u003c\/sup\u003e. It was also shown to markedly increase Akkermansia muciniphila.\u003csup\u003e9\u003c\/sup\u003e Animal models indicate a role for Akkermansia on gut barrier function, including increased mucus layer thickness and production of occludin, an essential component of tight junctions.\u003csup\u003e10\u003c\/sup\u003e Research suggests that polyphenols from blueberry and pomegranate support the growth of lactobacilli and bifidobacterium in the colon, as well as cytokine balance in the G.I. tract.\u003csup\u003e11*\u003c\/sup\u003e\u003c\/p\u003e\n\u003c\/div\u003e\u003c\/div\u003e\n\u003cdiv class=\"right\"\u003e\u003cdiv class=\"sub-content references\"\u003e\n\u003ch2\u003eReferences\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eNatalia S, et al. \u003cem\u003eNutrients.\u003c\/em\u003e 2018 May; 10(5): 576.\u003c\/li\u003e\n\u003cli\u003eLecerf JM, et. al. \u003cem\u003eBr J Nutr.\u003c\/em\u003e 2012 Nov 28;108(10):1847-58.\u003c\/li\u003e\n\u003cli\u003eChilds CE, et al. \u003cem\u003eBr J Nutr.\u003c\/em\u003e 2014 Jun 14;111(11):1945-56.\u003c\/li\u003e\n\u003cli\u003eDe Angelis M, et. al. \u003cem\u003eInt J Food Microbiol.\u003c\/em\u003e 2016 Dec 19;239:125-132.\u003c\/li\u003e\n\u003cli\u003eFinegold SM, et. al. \u003cem\u003eFood Funct.\u003c\/em\u003e 2014. 5; 436-445.\u003c\/li\u003e\n\u003cli\u003eZhaoping L, et. al. \u003cem\u003eInt J Food Sci Nutr.\u003c\/em\u003e 2015;66(8):919-22.\u003c\/li\u003e\n\u003cli\u003eRastall R. et al. \u003cem\u003eBJCN\u003c\/em\u003e, 2013, 109, 1980-1989. BioEcolians\u003csup\u003e®\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003eHowell K, et. al. \u003cem\u003eBiochem Biophys Res Commun.\u003c\/em\u003e 2018 Jul 12;502(2):238-242.\u003c\/li\u003e\n\u003cli\u003eVetrani C, et. al. \u003cem\u003eActa Diabetol.\u003c\/em\u003e 2020 Jul;57(7):853-860.\u003c\/li\u003e\n\u003cli\u003eAnh FF, et al. \u003cem\u003eGut\u003c\/em\u003e. 2015 Jun;64(6):872-83.\u003c\/li\u003e\n\u003cli\u003eFrug AD, et. al. \u003cem\u003eJ Acad Nutr Diet.\u003c\/em\u003e 2020 Apr;120(4):650-659\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003c\/div\u003e\u003c\/div\u003e\n\u003c\/div\u003e\u003c\/div\u003e\n\u003cdiv class=\"right\"\u003e\u003cdiv class=\"allergens\"\u003e\n\u003cdiv class=\"product-sixicons\"\u003eGluten Free; GMO Free; Vegan; Vegetarian\u003c\/div\u003e\n\u003cdiv class=\"product-sixicons\"\u003e\u003c\/div\u003e\n\u003cdiv class=\"product-sixicons\"\u003e\n\u003cdiv class=\"sub-content storage\"\u003e\n\u003ch2\u003eStorage\u003c\/h2\u003e\n\u003cp\u003eStore in a cool, dry place.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"right\"\u003e\u003cdiv class=\"sub-content source\"\u003e\n\u003ch2\u003eSource\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003ePreticX\u003csup\u003e™\u003c\/sup\u003e xylooligosaccharide (XOS) is derived from corn cob and purified to be free of corn protein\u003c\/li\u003e\n\u003cli\u003eBioEcolians\u003csup\u003e®\u003c\/sup\u003e a-glucooligosaccharide\u003c\/li\u003e\n\u003cli\u003e(a-GOS) is derived from sucrose\u003c\/li\u003e\n\u003cli\u003eCranberry extract is derived from \u003cem\u003eVaccinium macrocarpon\u003c\/em\u003e fruit and standardized to contain 12 mg proanthocyanidins (PACs)\u003c\/li\u003e\n\u003cli\u003eBlueberry extract is derived from \u003cem\u003eVaccinium angustifolium\u003c\/em\u003e fruit and standardized to contain 4% polyphenols\u003c\/li\u003e\n\u003cli\u003ePomegranate juice powder is derived from \u003cem\u003ePunica granatum\u003c\/em\u003e fruit\u003c\/li\u003e\n\u003cli\u003eCitric acid is derived from corn dextrose fermentation\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\u003c\/div\u003e\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cbr\u003e\n\u003cp\u003e\u003cstrong\u003eUnit Size:\u003c\/strong\u003e 138 gram powder\u003cbr\u003e\n\u003cstrong\u003eContraindications:\u003c\/strong\u003e If you are pregnant or lactating, have any health condition or are taking any medication, consult a healthcare professional before use.\u003c\/p\u003e\n\u003cbr\u003e\n\u003cp\u003e\u003cstrong\u003eIngredients\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eServing Size: 1 Scoop (Approximately 4.6 Grams) Servings Per Container: Approximately 30 Amount Per Serving % DV Calories 10 Total Carbohydrate 3g 1%† Total Sugars 2g * PreticX™ Xylooligosaccharide (XOS) 1.4g * BioEcolians® a-glucooligosaccharide (a-GOS) 1g * Cranberry (Vaccinium macrocarpon) Extract (Fruit) 1.2g *(Standardized to contain 12mg proanthocyanidins (PACs))Blueberry (Vaccinium angustifolium) Extract (Fruit) 100mg *(Standardized to contain 4% polyphenols)Pomegranate (Punica Granatum) Juice Powder (Fruit) 500mg * *Daily Value (DV) not established. †Percent Daily Values base on a 2‚000 calorie diet. Other Ingredients: Citric acid‚ malic acid‚ stevia leaf extract.\u003c\/p\u003e","brand":"Pure Encapsulations","offers":[{"title":"Default Title","offer_id":47461411684508,"sku":"P293A","price":31.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0473\/2407\/0044\/files\/poly-prebiotic-powder-pure-encapsulations.png?v=1787529018","url":"https:\/\/primenaturalfoods.ca\/fr\/products\/poly-prebiotic-powder","provider":"Prime Natural Foods","version":"1.0","type":"link"}