Inositol

• Helps to restore normal ovarian function, ovulation and oocyte quality
• Helps to normalize menstrual cycle irregularities
• Promotes healthy glucose metabolism

Women with PCOS experience various hormonal and metabolic conditions resulting from increased insulin production. For example, high levels of insulin can affect glucose metabolism and lead to weight gain. Insulin may also stimulate the secretion of male sex hormones in the ovaries. High levels of these hormones can lead to excessive hair growth, acne and abnormal ovulation. In addition, women often experience menstrual cycle irregularities and infertility. Inositol is a component of the B-complex family and is mainly found in the diet as myo-inositol. Research suggests that myo-inositol helps to manage these conditions by supporting healthy glucose metabolism. Myo-inositol also plays an important role in the inositol triphosphate second messenger system that regulates oocyte development and menstrual cycle hormones. Clinical trials involving women with PCOS have found that myoinositol supplementation decreases the time to first ovulation, reduces serum testosterone levels, increases ovulation frequency, and elevates estradiol levels (a marker of follicular maturation).